Pears are consumed fresh, canned, as juice, and dried. A species grown in western China, P. sinkiangensis, and P. pashia, grown in southern China and south Asia, are also produced to a lesser degree. Other small-fruited pears, distinguished by their early ripening and apple-like fruit, may be referred to as P. cordata, a species found wild in western France and southwestern England. Pear Therapeutics Announces FDA Submission for Somryst™, a Prescription Digital Therapeutic for the Treatment of Adults With Chronic Insomnia and Depression - Pear Therapeutics. According to Pear Bureau Northwest, about 3000 known varieties of pears are grown worldwide. Pear Therapeutics on Wikipedia, Google News & Yahoo Finance. [24], The culinary or cooking pear is green but dry and hard, and only edible after several hours of cooking. 'A Partridge in a Pear Tree' is the first gift in "The Twelve Days of Christmas" cumulative song. John Augustine Chilton Hearst (born October 24, 1952) is an American business and media executive, film producer and philanthropist. The Willow-leaved pear (Pyrus salicifolia) is grown for its attractive, slender, densely silvery-hairy leaves. [23] Refrigeration will slow further ripening. Pear Therapeutics is a provider of a software-based digital therapeutics platform designed to treat disease and enhance the efficacy of pharmaceuticals. Pear Therapeutics, a digital therapeutics company working on apps for substance use disorders, just lost a key partnership with Sandoz, the generics division of Novartis. Pear Bureau Northwest offers tips on ripening and judging ripeness: Although the skin on Bartlett pears changes from green to yellow as they ripen, most varieties show little color change as they ripen. Of these the fruit perishes not nor fails in winter or in summer, but lasts throughout the year.". One major difference is that the flesh of pear fruit contains stone cells. A free inside look at company reviews and salaries posted anonymously by employees. The idea is that software can improve a person’s health, without the … Pear Therapeutics, Inc. is a California Foreign Corporation filed on January 14, 2016. Pears may be stored at room temperature until ripe. 23 Pearl Therapeutics reviews. For new varieties the flowers can be cross-bred to preserve or combine desirable traits. © 2021 Pear Therapeutics, Inc. All Rights Reserved. We are leading the development of a new segment in the healthcare industry, prescription digital therapeutics, or PDTs. The company combines pharmaceutical therapy with software technology, such as digital applications and games. Salaries posted anonymously by Pear Therapeutics employees. The company's platform combines novel digital interventions with drugs to enhance efficacy well beyond anything that is commercially available or in clinical development, enabling clients to The juice can also be used in jellies and jams, usually in combination with other fruits, including berries. Exercise, dietary management, and the use of drugs, surgery, and psychotherapy are examples of therapeutic measures integral to disease prevention and treatment. Technology. Health Care. 08/21/2006. The pear was also cultivated by the Romans, who ate the fruits raw or cooked, just like apples. [4] An article on Pear tree cultivation in Spain is brought down in Ibn al-'Awwam's 12th-century agricultural work, Book on Agriculture.[5]. Fermented pear juice is called perry or pear cider and is made in a way that is similar to how cider is made from apples. History. Pearwood is the favored wood for architect's rulers because it does not warp. The Registered Agent on file for this company is C T Corporation System and is located at 818 West Seventh St … He plays a leadership role in the family-owned Hearst Corporation, one of America's largest diversified media companies where he has been a member of the board of directors since 1990. Pears were cultivated in China as early as 2000 BC. Every day, we push the boundaries of technology to transform medicine. Pear Therapeutics Inc. provides software for healthcare services. Pear Therapeutics on LinkedIn, Twitter & YouTube. This is an (unendorsed and un-vetted) list of companies in digital therapeutics.Digital therapeutics (DTx) deliver evidence-based therapeutic interventions to patients that are driven by high quality software programs to prevent, manage, or treat a broad spectrum of physical, mental, and behavioral conditions. [22] Ripe pears are optimally stored refrigerated, uncovered in a single layer, where they have a shelf life of 2 to 3 days.[22]. We operate at the intersection of biology and software technology, where researchers and clinicians work side-by-side with software engineers and developers to create the next generation of therapeutics. The pear is native to coastal and mildly temperate regions of the Old World, from Western Europe and North Africa east across Asia.It is a medium-sized tree, reaching 10–17 m (33–56 ft) tall, often with a tall, narrow crown; a few species are shrubby.. Things are looking up at Pear Therapeutics!The company announced the closure of a $64 million Series C financing barely a month after receiving the thumbs-up from the U.S. Food and Drug Administration (FDA) for reSET-O, its prescription software for the treatment of opioid use-related addiction disorder. This verse is repeated twelve times in the song. The pear is native to coastal and mildly temperate regions of the Old World, from Western Europe and North Africa east across Asia. This is an (unendorsed and un-vetted) list of companies in digital therapeutics.Digital therapeutics (DTx) deliver evidence-based therapeutic interventions to patients that are driven by high quality software programs to prevent, manage, or treat a broad spectrum of physical, mental, and behavioral conditions. He has served as a director or advisor to several companies, including Gridline Communications Holdings, Pear Therapeutics… Pearl Therapeutics is developing unique dual and triple combination products for the treatment of widely prevalent respiratory diseases, including chronic obstructive pulmonary disease. Pear wood is valued for kitchen spoons, scoops and stirrers, as it does not contaminate food with color, flavor or smell, and resists warping and splintering despite repeated soaking and drying cycles. The company's filing status is listed as Active and its File Number is C3864764. pyraster and P. c. subsp. The pear tree was an object of particular veneration (as was the Walnut) in the Tree worship of the Nakh peoples of the North Caucasus – see Vainakh mythology and see also Ingushetia – the best-known of the Vainakh peoples today being the Chechens of Chechnya. Pear has a pipeline of products and product candidates across therapeutic areas, including severe psychiatric and neurologic conditions. SAN FRANCISCO—Pear Therapeutics has posted $64 million in new fundraising on the heels of scoring an FDA clearance last month for its prescription software … … There are tons of interesting problems, for example how to design a study, how the FDA even regulates software, how to build products quickly, and how to get patient feedback. [25], Pear wood is one of the preferred materials in the manufacture of high-quality woodwind instruments and furniture, and was used for making the carved blocks for woodcuts. SECTOR. Lincoln[26] describes it as "a fairly tough, very stable wood... (used for) carving... brushbacks, umbrella handles, measuring instruments such as set squares and T-squares... recorders... violin and guitar fingerboards and piano keys... decorative veneering." Signs of the disorder include a strong desire to use opioids, increased tolerance to opioids, difficulty fulfilling obligations, trouble reducing use, and withdrawal symptoms with discontinuation. About Pearl Therapeutics. Pears grow in the sublime orchard of Alcinous, in Odyssey vii: "Therein grow trees, tall and luxuriant, pears and pomegranates and apple-trees with their bright fruit, and sweet figs, and luxuriant olives. CEO and President Dr. Corey McCann said that Somryst, a digital treatment for chronic insomnia and depression, is the first software as a medical device product to be submitted through the regulator's pilot pathway. Pear Therapeutics's latest funding round in December 2020 was reported to be $80 m. In total, Pear Therapeutics has raised $207.8 m Pears are fruits produced and consumed around the world, growing on a tree and harvested in late Summer into October. Pear and walnut trees were held to be the sacred abodes of beneficent spirits in pre-Islamic Chechen religion and, for this reason, it was forbidden to fell them. The tree is medium-sized and native to coastal and mildly temperate regions of Europe, North Africa, and Asia. Pear cultivation in cool, temperate climates extends to the remotest antiquity, and evidence exists of its use as a food since prehistoric times. Pear Therapeutics is a pioneer of so-called digital therapeutics, having gained the first ever such approval from the FDA in 2017, for its treatment for patients with Substance Use Disorder (SUD). communis), are without doubt derived from one or two wild subspecies (P. c. subsp. Other species are used as rootstocks for European and Asian pears and as ornamental trees. [citation needed] The enormous number of varieties of the cultivated European pear (Pyrus communis subsp. Pear Therapeutics director outlines challenges of regulated software design MobiHealthNews 4/04/19 Pharma Giants Like Novartis and Sanofi Are Betting That The Futre of Healthcare Looks More Like an App or Sensor Than a Prescription Business Insider 2/20/19 The fruit of the pear is produced on spurs, which appear on shoots more than one year old.[11]. Pearl Therapeutics is a privately held company developing inhaled combination therapies for the treatment of highly prevalent respiratory diseases, including chronic obstructive pulmonary disease and asthma. the nashi pear. Summer and autumn cultivars of Pyrus communis, being climacteric fruits, are gathered before they are fully ripe, while they are still green, but snap off when lifted. In a 100 g reference amount, raw pear supplies 57 kilocalories, a moderate amount of dietary fiber, and no other essential nutrients in significant amounts (table). In 2018, world production of pears was 23.7 million tonnes, led by China with 68% of the total (table). As a partner and board member, Mr. Smith is actively involved in a number of medical and green technology businesses, including Emlink, which develops, designs and manages sustainable technology; The Marwood Group, a healthcare-focused strategic advisory and financial services firm; and Pear Therapeutics, a medical software company. FOUNDED. Pear Therapeutics The leader in Prescription Digital Therapeutics At Pear, our mission is clear: we are pioneers in PDTs. Our cross-functional team operates at the … [10] About 3000 known varieties of pears are grown worldwide, which vary in both shape and taste. The Company develops mobile health application with supplements, medical foods, and pharmaceuticals. communis cultivated mainly in Europe and North America, the Chinese white pear (bai li) Pyrus × bretschneideri, and the Nashi pear Pyrus pyrifolia (also known as Asian pear or apple pear), both grown mainly in eastern Asia. Raw pear is 84% water, 15% carbohydrates and contains negligible protein and fat (table). If it yields to gentle pressure, then the pear is ripe, sweet, and juicy. Many traces have been found in prehistoric pile dwellings around Lake Zurich. The word pear is probably from Germanic pera as a loanword of Vulgar Latin pira, the plural of pirum, akin to Greek apios (from Mycenaean ápisos),[1] of Semitic origin (pirâ), meaning "fruit". Three species account for the vast majority of edible fruit production, the European pear Pyrus communis subsp. Pear Therapeutics discovers, develops, and delivers clinically-validated software-based therapeutics to provide better outcomes for patients, smarter engagement and tracking tools for clinicians, and cost-effective solutions for payers. Zack Lynch is an entrepreneur, market maven and futurist who brings a rich understanding of the technologies and companies driving the experiential technology market to JAZZ. BlackThorn Therapeutics is a clinical-stage biopharmaceutical company developing novel, targeted treatments for neurobehavioral disorders. If it is firm, leave the pear at room temperature and check daily for ripeness. Pear has a great ambition to produce digital therapeutics to treat all kinds of medical conditions. Most pears are deciduous, but one or two species in Southeast Asia are evergreen. Pear Therapeutics' digital insomnia therapeutic will put FDA's PreCert framework through its paces. Every day, we push the boundaries of technology to transform medicine. Therapeutics, treatment and care of a patient for the purpose of preventing and combating disease or alleviating pain or injury. The fruit is composed of the receptacle or upper end of the flower stalk (the so-called calyx tube) greatly dilated. Pearl Therapeutics serves customers in the United States. The genus is thought to have originated in present-day Western China[8] in the foothills of the Tian Shan, a mountain range of Central Asia, and to have spread to the north and south along mountain chains, evolving into a diverse group of over 20 widely recognized primary species. Asian species with medium to large edible fruit include P. pyrifolia, P. ussuriensis, P. × bretschneideri, P. × sinkiangensis, and P. pashia. Several species of pears are valued for their edible fruit and juices, while others are cultivated as trees. Based in Philadelphia, Aro Biotherapeutics is a biotechnology company pioneering the development of tissue-targeted genetic medicines with a platform based on a proprietary protein technology called Centyrins. Health Care. It is similar to the wood of its relative, the apple tree (Malus domestica) and used for many of the same purposes.[26]. Pear is a place for pioneers: for those with a passion for investigating unchartered territories and boldly advancing medicine and patient treatments. Pears and apples cannot always be distinguished by the form of the fruit;[3] some pears look very much like some apples, e.g. Pearl Therapeutics | 3,727 followers on LinkedIn. 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